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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11380 | GDC-0927 | SRN-927 | Others |
GDC-0927 is a novel,non-steroidal, potent, orally bioavailable, selective estrogen receptor antagonist. | |||
T13700 | GDC-0927 Racemate | SRN-927 Racemate | Others |
GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM. | |||
T39916 | GNE-274 | ||
GNE-274, a non-degrader compound structurally similar to GDC-0927 (an ER degrader), serves as a partial ER agonist in breast cancer cell lines without triggering ER turnover. Notably, GNE-274 enhances chromatin accessibi... |